あなたの研究テーマについて教えてください。What is your research theme?
My research focuses on protein oligomerization, the process by which multiple protein molecules assemble into larger complexes. This mechanism plays a fundamental role in biological systems, regulating enzyme activity, enabling cell-to-cell communication, and providing structural support.
In particular, I investigate the oligomerization of hemoglobin (Hb), a tetrameric oxygen carrier protein in red blood cells composed of four polypeptide chains, each containing a heme group. Previous studies suggest that Hb can associate into higher-order oligomers beyond its tetrameric state, which may affect its oxygen-binding capacity and contribute to certain diseases. However, the detailed mechanism of hemoglobin oligomerization remains unclear.
To address this gap, my research aims to reveal the structural basis of Hb oligomerization through three-dimensional structural analysis. To date, I have successfully purified and crystallized a prospective dimer derived from the Hb tetramer and evaluated its structural properties. The determination of its atomic structure is expected to be determined by X-ray crystallography.
The outcomes of this study are expected to provide new insights into the fundamental principles of protein–protein interactions. In the long term, these findings may contribute to advances in protein engineering and the development of novel functional biomaterials.
なぜ博士課程へ進学しましたか？Why did you decide to pursue a doctoral program?
My interest in science began at an early age, particularly during elementary school, when I developed a deep curiosity about natural phenomena, especially those related to living organisms. Through reading books, I often found myself asking questions such as how plants produce oxygen through photosynthesis, how animals adapt to their environments, and how human organs function.
As I advanced in my studies, I gradually found answers to many of the questions. This experience made me realize that knowledge not only satisfies curiosity but also provides the foundation for creating innovations that benefit society. In addition, I have also been inspired by scientists whose research has led to the discoveries with profound societal impact, which further deepened my love for science and learning.
During my university education, I chose to study biology because of its direct relevance to human life and its potential to elucidate how biological systems function within us. Through this path, I gained valuable experience in molecular biology research, particularly in areas related to infectious diseases, genetic disorders, and cancer. These experiences were both valuable and eye-opening, as they highlighted the complexity of biological systems and the many challenges that remain unresolved. This realization inspired me to pursue a deeper understanding of life at the molecular level and motivated me to engage in more advanced research to address these challenges.
I decided to continue my academic journey by pursuing a doctoral degree, driven by my passion for scientific inquiry. Through this path, I aim to deepen my knowledge, refine my expertise, and further develop the skills and experiences necessary to broaden my scientific impact. I am particularly drawn to Japan for its globally recognized research excellence, supportive academic environment, and strong commitment to innovation. I believe that conducting my doctoral research in Japan will not only provide advanced training and international exposure but also enable me to make meaningful contributions to both science and society.
Graniteの支援で役立っている・助かっていることを教えてください。Please share what has been helpful or beneficial through the support provided by Granite.
Receiving the Granite Scholarship has been an invaluable support for both my academic and personal life. The financial assistance has allowed me to focus more fully on my research without the constant concern of living expenses, which is particularly important as I live in Japan with my family. This support has created a stable environment in which I can dedicate my energy and attention to advancing my doctoral research.
Beyond financial aid, the Granite Scholarship has provided numerous opportunities that have enriched my academic and professional development. I have a chance to participate in lab internships, attend seminars and workshops, and receive career consultation. Overall, the scholarship has had a profound impact on my research journey, enabling me to pursue my studies with greater focus, confidence, and engagement in the broader scientific community.
将来の目標、もしくはあなたが胸に秘めた野望があればぜひ教えてください。Please share your future goals or any ambitions you hold close to your heart.
I am eager to advance my academic and professional journey with the aspiration of making meaningful contributions to both science and society. My long-term goal is to apply my expertise to deepen scientific understanding while also developing practical solutions to address real-world challenges.
I believe that impactful research should not remain confined to the laboratory but should also contribute to improving people’s lives and advancing society as a whole. Through this path, I hope to grow as a researcher who not only expands the frontiers of science but also delivers meaningful impact for future generations.
博士課程進学を考えている人へのメッセージをください。Please share a message for those considering pursuing a doctoral program.
Pursuing a doctorate is more than an academic decision—it is a life decision. It is a path not only filled with curiosity, discovery, and personal growth, but also with challenges that test your patience, resilience, and belief in yourself.
There will be moments of excitement when your ideas take shape, and there will also be times of doubt when progress feels slow. Both are natural parts of the journey. What matters most is remembering why you chose this path in the first place—your passion for knowledge, your desire to make a difference, and your dream of contributing something meaningful to the world.
A doctoral journey is not one you walk alone. Seek guidance from mentors, lean on family and friends, and embrace the community around you. Their support will remind you that you are capable, even when the road feels difficult.
If you are considering this path, step forward with courage, clarity, and an open heart. It may be one of the most challenging chapters of your life, but it can also be one of the most rewarding experiences.
